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Last Updated: 2 years ago

Possible Interaction: Ethanol and Ascorbate





Research Papers that Mention the Interaction

These results indicate that ethanol stimulates the capacity to synthesize ascorbate which, in turn, causes an increase of ascorbic acid contents in the urine and soft tissues.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine  •  1982  |  View Paper
This is due to the participation of ascorbate in oxidoreducing processes connected with ethanol metabolism which leads to its irreversible destruction.
Physiological research  •  1995  |  View Paper
It was found that systemic application of ethanol induced brain ascorbate ( AA ) release.
Neuroscience Letters  •  1994  |  View Paper
The results suggest that ethanol-evoked release of AA probably is a self-protective mechanism against the neurotoxicity induced by ethanol in the brain, and the NMDA receptor may play an important role in this mechanism.
Neuroscience Letters  •  1993  |  View Paper
4-Methylpyrazole (50 mg/kg, IP), which inhibits alcoholdehydrogenase, could not prevent the increase in AA concentration, evoked by ethanol.
A single injection of ethanol , 1.0 g/kg intraperitoneally (IP), induced a significant increase in extracellular AA concentration in both the nucleus accumbens and striatum.
Alcohol  •  1992  |  View Paper
The ethanol load induces also a decrease in the cerebellar concentration of the three main endogenous anti-oxidant small molecules, i.e. alpha-tocopherol, ascorbate and glutathione.
Alcohol and alcoholism (Oxford, Oxfordshire). Supplement  •  1987  |  View Paper
Moderate concentrations of ethanol reduce the velocity of uptake of three representative Na+‐symport systems (D‐glucose, L‐alanine, L‐ascorbate ), whether electrogenic (the first two) or electroneutral (L‐ascorbate).
FEBS letters  •  1986  |  View Paper
In the presence of copper, ethanol protected at [ascorbate] less than 1 mM, but was ineffective at [ ascorbate ] greater than 2 mM, even in the absence of oxygen.
The Journal of biological chemistry  •  1986  |  View Paper
Ethanol treatment enhanced lipid peroxidation significantly, depletion in levels of hepatic glutathione and ascorbate , accompanied by a decline in the activities of glutathione peroxidase and glutathione reductase, and increased in hepatic glutathione s-transferase activity.
Indian Journal of Clinical Biochemistry  •  2008  |  View Paper
Ethanol increases ascorbate retention.
Journal of bioenergetics and biomembranes  •  1995  |  View Paper
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