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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Ethanol and Aripiprazole



Research Papers that Mention the Interaction

As the effects of most drugs of abuse converge to enhance dopamine‐mediated neurotransmission, the present study was designed to test the hypothesis that aripiprazole would inhibit the acute effects of ethanol , a widely abused substance.
The present data lead to the conclusion that aripiprazole prevents the stimulant effects of ethanol on locomotion, without interfering with the motor impairment induced by this drug.
Basic & clinical pharmacology & toxicology  •  2013  |  View Paper
ARI also significantly attenuated the ethanol induced reduction in the levels of gastric wall mucus, and NP-SH (P < 0.001).
ARI showed significant antiulcer and gastroprotective activity against ethanol induced gastric ulcers.
Ethanol induced depletion in the levels of serotonin in the gastric tissue were also significantly restored by pretreatment with ARI (p < 0.001).
Pretreatment with ARI significantly (P < 0.001), reduced the gastric lesions induced by ethanol and also resulted in a significant decrease in the gastric secretion, and total acidity in pylorus ligated rats.
International journal of clinical and experimental medicine  •  2014  |  View Paper