Possible Interaction: Ethanol and Antihypertensive Agents

“The interaction of alcohol with antihypertensive drugs requires further investigation as hypertensive patients who consume alcohol regularly are known to have less adequate blood pressure control.”

“In urban area, hypertensives were less physically active, and more likely to smoke and consume alcohol.”

“Some antihypertensive drugs affect oxidative stress and endothelial function and might counteract the effects of alcohol at the cellular level.”

“The subjects had low self-efficacy about how to prevent interactions of antihypertensives with OTC analgesics and alcohol.”

“ Ethanol led to nocturnal drops of blood pressure in normotensives and hypertensives alike and thus to an increased day/night difference.”

“Because of its significant pressor effect, alcohol should be avoided by hypertensives.”

“Aspects of nutrition play an important role in the aetiology and non-pharmacological treatment of hypertension, for which the following are recommended: (i) obese … the optimal level of dietary intake of salt; (iii) foods rich in potassium should be recommended; and (iv) alcohol intake should be moderate; hypertensives … ethanol ….”

“The use of alcohol was associated, especially in men, with poor compliance with antihypertensive medication.”

“ Hypertensives reported a … of alcohol and higher noncompliance in taking prescribed medicines by a randomized response technique with a dichotomous response as compared with direct response, and … week, but similar compliance in taking prescribed medicines, by a randomized response technique with a quantitative response as compared with direct response.”

“Perceived interaction between alcohol and antihypertensive medication was reported by 9.9% of patients but the symptoms were rather mild.”