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Last Updated: 3 years ago

Possible Interaction: Ethanol and Antidepressive Agents

Research Papers that Mention the Interaction

Both these antidepressants were felt to be sedative, especially in the initial phase of the treatment, and they interacted additively with ethanol.
European Journal of Clinical Pharmacology  •  2004  |  View Paper
Antidepressants alone had no effect on psychomotor skills, but alcohol always impaired performance.
European Journal of Clinical Pharmacology  •  2004  |  View Paper
It was found that the tricylic antidepressant added to the deleterious effects of alcohol.
Science  •  1969  |  View Paper
However, despite the fact that benzodiazepines possess high therapeutic index and are … safe, their use can be dangerous when: (1) co-administered with alcohol , (2) co-… like sedatives, antidepressants , neuroleptics or morphine like substances, (3) driving under their influence, (…-therapeutically as drugs of abuse or in drug-facilitated crimes.
Journal of pharmaceutical and biomedical analysis  •  2015  |  View Paper
Alcohol , cocaine or benzodiazepines when concomitantly consumed with antidepressant treatment may increase the risk for acting out.
Presse medicale  •  2013  |  View Paper
Precautions necessary with any depressant agent should be followed, including a warning to patients about the likely additive effects of alcohol and other depressant drugs, and the possibility of residual effects on performance in the morning.
Drugs  •  2012  |  View Paper
However, even in the presence of co-occurring depression, antidepressants in general lack the power to demonstrate a significant reduction of alcohol use among alcohol dependent patients with carefully diagnosed major depression.
Current pharmaceutical design  •  2010  |  View Paper
Many of these medications had the potential for adverse interactions with alcohol , including opioids, anxiolytics, antidepressants , hypnotics, antipsychotics, and mood regulators.
The American journal of emergency medicine  •  2019  |  View Paper
Conclusions The present case report suggests that there may be an interaction between alcohol and antidepressants resulting in the serotonin syndrome, and clinicians should be aware of this possibility.
Clinical neuropharmacology  •  2019  |  View Paper
There was no difference for other relevant outcomes such as the … -0.12 to 0.42).Moderate-quality evidence found that antidepressants … alcohol during the trial (7 studies, 424 participants, RR 1.71, 95% Cl 1.…) -1.13 drinks per drinking days, 95% Cl -1.79 to -0.46).
The Cochrane database of systematic reviews  •  2018  |  View Paper
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