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Last Updated: 3 years ago

Possible Interaction: Ethanol and Anti-Arrhythmia Agents

Research Papers that Mention the Interaction

Possible mechanisms for the cardiac depression that followed the administration of ethyl alcohol are discussed.
American heart journal  •  1967  |  View Paper
Alcohol also altered peripheral clock gene amplitude of peripheral blood mononuclear cells in CLOCK, BMAL, PER1, CRY1, and CRY2 in both groups, and inflammatory markers lipopolysaccharide-binding protein, LPS, and IL-6 had an elevated mesor at baseline in NW vs. DW and became arrhythmic with alcohol consumption.
American journal of physiology. Gastrointestinal and liver physiology  •  2016  |  View Paper
Although alcohol has long been known to induce cardiac depression and cardiomyopathy, it is not known whether drug therapy or pharmacologic manipulation can be used to prevent or reverse these toxicities.
Magnesium and trace elements  •  1991  |  View Paper
These findings could help to explain why alcohol can induce cardiac depression , arrhythmias, cardiomyopathy and the higher than normal incidence of sudden death observed in ‘binge’ drinkers.
British journal of pharmacology  •  1983  |  View Paper
Alcohol significantly dampened diurnal rhythms of mRNA levels in clock genes Bmal1 and Dbp, phase advanced Nr1d1/REV-ERBα, and induced arrhythmicity in Clock, Noct, and Nfil3/E4BP4, with further disruption in livers of LKO mice.
Frontiers in Physiology  •  2020  |  View Paper