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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Ethanol and Amprenavir



Research Papers that Mention the Interaction

However, ethanol significantly decreased the IC(50) of type II PIs, indinavir and ritonavir, and markedly increased the IC(50) of amprenavir and darunavir.
Alcoholism, clinical and experimental research  •  2011  |  View Paper
A low concentration of the NMDA antagonist APV (5 μm) mimicked the inhibition of ethanol of persistent activity with no change in activity after washout.
The Journal of Neuroscience  •  2007  |  View Paper
Preincubation of the slices with 25 microM APV reduced the relative degree of inhibition caused by EtOH suggesting that N-methyl-D-aspartate (NMDA)-receptor-mediated events can be affected by EtOH.
Journal of neurophysiology  •  2000  |  View Paper
On the other hand, the nicotine + ethanol combination increased APV and caused attenuation of the excitatory effects of nicotine in dogs.
Journal of cardiovascular pharmacology  •  1998  |  View Paper