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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Ethanol
drug:
Amobarbital
Research Papers that Mention the Interaction
“ Amylobarbitone and flurazepam also enhanced the alcohol induced impairment of co-ordinative skills.”
Effect of subacute treatment with hypnotics, alone or in combination with alcohol, on psychomotor skills related to driving.“A sub-hypnotic dose of ethanol increased the volume of distribution of amylobarbitone and the consequent reduction in fractional elimination prolonged the half-life of the hypnotic.”
“The presence and mechanism of synergism of action between ethanol and amylobarbitone , phenobarbitone or methaqualone was determined by application of simple pharmacokinetic models to log dose-response curves and plasma concentration-time curves for the hypnotics alone or when ethanol was given concurrently.”
Interaction of ethanol with amylobarbitone, phenobarbitone and methaqualone.“The simultaneous administration of ethanol at doses of either 2, 3, or 4 g/kg intraperitoneally produced a dose-related decrease in the intraperitoneal LD50 for thiopentone, pentobarbitone, amylobarbitone , phenobarbitone and barbitone in rats.”
“The simultaneous administration of ethanol at doses of either 2, 3, or 4 g/kg intraperitoneally produced a dose‐related decrease in the intraperitoneal LD50 for thiopentone, pentobarbitone, amylobarbitone , phenobarbitone and barbitone in rats.”
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