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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Ethanol
drug:
Aminophylline
Research Papers that Mention the Interaction
“In conclusion, the effects of ethanol were inhibited by its association with aminophylline , suggesting that ethanol acts on the adenosine neurotransmission.”
Aminophylline (a theophylline–ethylenediamine complex) blocks ethanol behavioral effects in mice“Withdrawal from the ethanol chronic treatment increased the thresholds to seizures produced by intravenous aminophylline ; this change was also prevented by nitrendipine.”
“Dibutyryl … aminophylline and papaverine, and adenosine (which stimulates adenyl cyclase) all caused a variable increase in uptake of norepinephrine at concentrations ranging … 10−4 M. Prostaglandins E1 and E2 appeared to have no effect on uptake, but this may be because the alcohol required to dissolve … effect on uptake.”
“On the contrary, the association of ethanol and aminophylline increased the norepinephrine and dopamine content, while it decreased DOPAC when compared to the ethanol group, confirming the alterations observed in the behavioral tests.”
Antidepressant Effect of Aminophylline After Ethanol Exposure
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