Possible Interaction: Ethanol and Alprenolol

“At low ethanol concentrations, where the rate of ethanol metabolism seemed to be limited by the rate of re-oxidation of NADH, ethanol metabolism was markedly stimulated by the addition of alprenolol , propranolol or hexobarbital.”

“The increased lactate/pyruvate ratio caused by ethanol metabolism in isolated liver cells was decreased by the addition of alprenolol.”

“The present findings indicate that during simultaneous metabolism of ethanol and alprenolol , at low concentrations of ethanol, electrons can be diverted from the greatly reduced NADH/NAD+ couple by the microsomal monooxygenase reaction.”