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“In the rat, administration of ethanol as 36% of total calories for 4--6 wk produced a threefold rise in plasma AANB associated with a sixfold increase in hepatic AANB.”
“Interactions between ethanol and synaptic transmission mediated by gamma -amino-N-butyric acid ( GABA ) have been suggested to contribute to alcohol intoxication.”
“These findings indicate that ethanol potentiates GABA release, most likely via a direct action on presynaptic boutons.”