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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Ethanol
drug:
Aldosterone
Research Papers that Mention the Interaction
“ Aldosterone significantly increased after 6- and 12-month ethanol self-administration.”
A Relationship between the aldosterone - mineralocorticoid receptor pathway and alcohol drinking: preliminary translational findings across rats, monkeys and humans“The presence of alcohol in persons without hypertension resulted in a significant increase in aldosterone concentration in sudden cardiac death as compared to those with hypertension.”
“ Plasma aldosterone concentration decreased during ethanol intoxication, but increased greatly during hangover.”
“These findings are consistent with the hypotheses that (1) alcohol withdrawal results in a “… antidiuretic hormone activity, following prolonged suppression of ADH by continuous drinking, (2) increased aldosterone activity occurs during continuous drinking but … the opposing effects of ethanol ; it is suggested that when … the aldosterone effect becomes evident.”
“The effects of aldosterone and dexamethasone on (Na+K)-ATPase activity were augmented by ethanol in 50 and 19% of controls, respectively.”
“These results suggest that ethanol treatment enhances the upregulation of (Na+K)-ATPase activity by both aldosterone and dexamethasone, in cultured renal papillary collecting duct cells.”
Effect of ethanol on regulation of (Na+K)-adenosine triphosphatase by aldosterone and dexamethasone in cultured renal papillary collecting duct cells“30% ethanol inhibited secretion of glucagon, insulin and aldosterone.”
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