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Last Updated: 3 years ago

Possible Interaction: Ethanol and Aldesleukin



Research Papers that Mention the Interaction

Ethanol decreased TSF in a dose and route‐dependent manner.
We conclude that ethanol (and/or its metabolites) reduces TSF via humoral and neural mechanisms involving vagal pathways, muscarinic receptors and nitric oxide.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society  •  2007  |  View Paper
Serum levels of IL-2 and TNF-alpha were markedly higher than those of ethanol group and saline groups (P<0.05).
World journal of gastroenterology  •  2003  |  View Paper
Interleukin 2 synthesis by murine splenocytes was inhibited by ETH in a concentration-related manner; the lowest concentrations of ETH caused an increase in interleukin 2 synthesis.
Drug and alcohol dependence  •  1989  |  View Paper
The present work examines the mechanisms underlying ethanol-induced dysfunction of CD4(+) T lymphocytes based on the hypothesis that ethanol downregulates lipid raft-mediated TCR signal transduction and resultant IL-2 production.
Alcoholism, clinical and experimental research  •  2011  |  View Paper
However, the capacity of exogenously supplied IL-2 to stimulate proliferation of T cells that had previously acquired IL-2 receptors was suppressed by ethanol in a dose-dependent manner, and this suppression was monophasic.
Cellular immunology  •  1986  |  View Paper
Using a combination of pharmacology, optogenetics, and phenotypic analyses we determine that ethanol activates a Gαs-cAMP-protein kinase A signaling pathway in IL2 neurons to stimulate nematode locomotion.
Genetics  •  2017  |  View Paper
It was … their ethanol intoxication (13 days; total dose, … of blood cytokines IFNgamma, IL-2 , IL-4, IL-10, increases the concentration of IL-6, suppresses the immune responses, and reduces the … to the control, which testifies to the greater damage of Th1 cells in comparison to Th2 lymphocytes.
Eksperimental'naia i klinicheskaia farmakologiia  •  2010  |  View Paper
Ethanol consumption resulted in a reduction of the production of IL-2 , IL-4, and IL-6 as well as the basal and cytokine-activated NK cell cytolytic activity and IFN-gamma production in splenocytes.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research  •  2010  |  View Paper
The net result of changes in TLR‐mediated and co‐stimulatory signals may determine the altered immunological status induced by acute consumption of alcohol.
Scandinavian journal of immunology  •  2009  |  View Paper
BACKGROUND Chronic administration of ethanol increases plasma prolactin levels and enhances estradiol's mitogenic action on the lactotropes of the pituitary gland.
Alcoholism, clinical and experimental research  •  2008  |  View Paper
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