Possible Interaction: Ethanol and Adrenergic Antagonists

“…:Chronic ethanol ingestion by … high‐affinity β‐adrenergic agonist binding sites and a significant decrease in activation of adenylate cyclase by guanine nucleotides and β‐adrenergic agonists in the … was noted in the total number of β‐adrenergic receptors, as defined by the binding of the antagonist [125I]iodocyanopindolol.”

“The same concentrations of ethanol produced a dose‐dependent inhibition of the cardiac response to field stimulation of the adrenergic nerve terminals.”