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Discover Supplement-Drug Interactions
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Last Updated: 2 months ago
Research Papers that Mention the Interaction
“Possible esterification of acitretin to etretinate in the presence of ethanol has been reported.”
Acitretin is converted to etretinate only during concomitant alcohol intake“100 days), since acitretin is potentially esterified in vivo by ethanol into etretinate [4, 5].”
“With monkey and dog cells, traces of etretinate were found without ethanol addition, but the esterification of acitretin was highly enhanced by ethanol.”
“With rat and human hepatocytes, etretinate was detectable only when ethanol was co-administered with acitretin.”
“Co-administration of acitretin and ethanol to rats resulted in a maximum plasma concentration of etretinate at approximately 1 h after dosing.”
“The results of our study in the rat could indicate that the presence of etretinate in plasma of some patients being treated with acitretin may result from the intake of alcohol.”
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