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Last Updated: 3 months ago

Possible Interaction: Ethanol and Acetovanillone



Research Papers that Mention the Interaction

Apocynin prevented both the decreased in acetylcholine‐induced relaxation and intracavernosal pressure induced by ethanol.
Apocynin prevented the effects of ethanol on protein expression and p47phox translocation.
Ethanol increased superoxide anion (O2‐) generation and catalase activity in CSM, and treatment with apocynin prevented these responses.
Male Wistar rats were treated with ethanol (20% v/v) or ethanol plus apocynin (30 mg/kg/day; p.o.
European journal of pharmacology  •  2017  |  View Paper
Ethanol consumption increased superoxide anion (O2 (-)) generation and lipid peroxidation and apocynin prevented these responses.
Ethanol increased the expression of Nox1, PKCδ, nNOS, SAPK/JNK and SOD2 in the rat aorta and apocynin prevented these responses.
Alcohol and alcoholism  •  2016  |  View Paper
Ethanol consumption increased superoxide anion (O2−) generation and decreased nitrate/nitrite (NOx) concentration in the rat MAB and apocynin prevented these responses.
Journal of Physiology and Biochemistry  •  2016  |  View Paper
Pretreatment of hepatocytes with N-acetyl cystein (ROS reducer), or dietary antioxidants (quercetin, reserveratrol), or NADPH (reduced nicotinamide adenine dinucleotide phosphate) oxidase inhibitor apocynin , significantly reduced ethanol (50 mM, 24 h) induced increases in ROS and H3AcK9.
Alcohol  •  2010  |  View Paper
These beneficial effects were attenuated by apocynin treatment coincident with ethanol administration.
Free radical biology & medicine  •  2007  |  View Paper
The inhibition of reactive oxygen species by the intraperitoneal injection of apocynin attenuated renal fibrosis and restored renal function in the alcoholic mice.
Clinical science  •  2020  |  View Paper
Interestingly, treatment with the NADPH inhibitor, apocynin , significantly prevented oxidative stress, mitochondrial dysfunction, and the impairment of synaptic vesicle activity induced by ethanol treatment.
Neuropharmacology  •  2020  |  View Paper