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“Chemical treatments like QUE and POL reduced behavioral defects induced by ethanol exposure.”
“In conclusion, this study presents new evidence that QUE, POL , FA and their mixtures partially protected epiboly, teratogenic, and behavioral defects induced by ethanol exposure.”
Neurotoxicology and teratology • 2020 | View Paper
“Here, polydatin strongly alleviated hepatic steatosis and decreased the expression levels of alcohol and lipid metabolism-related genes, including CYP2Y3, CYP3A65, HMGCRa, HMGCRb and FASN.”
Journal of pharmacological sciences • 2018 | View Paper
“Simultaneously, polydatin pre-treatment also prevented alcohol induced mitochondrial damage and refurbished the matrix metalloproteinases levels of the hepatic tissue.”
Phytomedicine : international journal of phytotherapy and phytopharmacology • 2017 | View Paper
“ Polydatin reversed the performance impairments in chronic ethanol treated rats in Morris water maze test, and decreased unregulated Cdk5 expression.”