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Last Updated: 3 years ago

Possible Interaction: Ethanol and 1,3-Dpcpx



Research Papers that Mention the Interaction

We further show that a selective antagonist of A1 adenosine receptors, 8‐cyclopentyl‐1,3‐dipropylxanthine DPCPX ), blocks effects of 1–10 mm ethanol on synaptic transmission.
The European journal of neuroscience  •  2017  |  View Paper
Though withdrawal from 10 day EtOH exposure produced no toxicity in either male or female slice cultures, exposure to DPCPX during 24 hours of EtOH withdrawal produced a marked increase in PI uptake in all hippocampal culture subregions in female cultures (to approximately 160% of control values).
Alcoholism, clinical and experimental research  •  2008  |  View Paper
Intracerebellar microinfusion of adenosine A(1) agonist, N(6)-cyclohexyladenosine (CHA: 4 ng), and antagonist, 8-cyclopentyl-1,3-dipropylxanthine (DPCPX: 100 ng) markedly accentuated and attenuated, respectively, ethanol ataxia consistent with our previously published data.
Brain research bulletin  •  2006  |  View Paper
Pre-treatment with the adenosine A(1) receptor antagonist DPCPX (5 mg/kg, intraperitoneally) attenuated ethanol (2.5 g/kg, orally)-induced motor incoordination.
Basic & clinical pharmacology & toxicology  •  2004  |  View Paper
DPCPX abolished the protective effects of ethanol pretreatment (30+/-3%; n=7) but had no effect in dogs that did not receive ethanol (25+/-2%; n=7).
International journal of cardiology  •  2003  |  View Paper
Similarly, the highest intra-striatal dose of Ro15-4513 or DPCPX neither altered motor coordination or locomotor activity indicating relative selectivity of interaction with ethanol.
Brain Research Bulletin  •  2001  |  View Paper
Intrastriatal microinfusion of adenosine A1 receptor agonist N6-cyclohexyladenosine (CHA) and antagonist 8-cyclopentyl-1,3-dipropylxanthine DPCPX ), significantly accentuated and attenuated, respectively, the motor incoordinating effect of ethanol while having no effect on the normal motor coordination in saline-treated control animals.
Brain Research  •  1997  |  View Paper