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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
drug:
Ethacrynic Acid
supplement:
Tretinoin
Research Papers that Mention the Interaction
“The differentiation of HL-60 cells induced by all-trans retinoic acid , dimethyl sulfoxide or phorbol-12-myristate 13-acetate was also enhanced by ethacrynic acid with increasing NBT-reducing and lysozyme activities and the expression of CD11b or CD14 surface antigen.”
Ethacrynic acid and 1 alpha,25-dihydroxyvitamin D3 cooperatively inhibit proliferation and induce differentiation of human myeloid leukemia cells.“However, RA increased the percentage of EA rosetting promyelocytes of HL‐60 and of patients with acute promyelocytic leukemia and a part of myeloblasts isolated from acute myelogenous leukemia patients.”
“ RA suppressed IgG‐coated erythrocyte ( EA ) rosette formation of myelomonocytic cells blocked at relatively late stages of differentiation such as ML‐1, U‐937, THP‐1‐T, normal monocytes, and fresh cells of patients with acute myelomonocytic leukemia.”
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