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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Ethacrynic Acid
supplement:
Potassium
Research Papers that Mention the Interaction
“In the case of ethacrynic acid, potassium appears to diminish the rate of combination of the drug with the transport system.”
“The active potassium influx in the human red blood cell is inhibited by strophanthidin, ethacrynic acid , and MK-870 (a new diuretic), and the degree of inhibition is greater at low concentrations of extracellular potassium than at high.”
Concentration dependence of active potassium transport in the human red blood cell in the presence of inhibitors.“ ECA promotes potassium secretion probably by inhibiting cellular anion entry at the luminal membrane.”
Functional differences of ouabain and ethacrynic acid on renal potassium metabolism in dogs.“Furosemide, ethacrynic acid and hydrochlorothiazide each increased potassium excretion to near 20 microEq/min.”
“It is assumed from the results that EA abolishes activity of the positive electrogenic K+ pump and reduces the passive permeability of the walls of the cochlear duct to the potassium ions.”
“ Ethacrynic acid and furosemide appear to inhibit both reabsorption and secretion of potassium.”
“ Ethacrynic acid , when administered to six dogs, caused a fall in the concentration of potassium in endolymph from 145 to 21 milliequivalents per liter and a rise in the concentration of sodium from 5.9 to 146 milliequivalents per liter.”
“Intravenous administration of large doses of ethacrynic acid to rats enhanced the excretion of sodium, potassium and chloride in the urine.”
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