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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Estrone Sulfate
supplement:
Hesperetin
Research Papers that Mention the Interaction
“Eight major flavonoids (naringin, naringenin, hesperidin, hesperetin , phloridzin, phloretin, quercetin, and kaempferol) contained in the juices inhibited OATP2B1-mediated estrone-3-sulfate uptake with IC(50) values of 4.63, 49.2, 1.92, 67.6, 23.2, 1.31, 9.47, and 21.3 µM, respectively.”
Major active components in grapefruit, orange, and apple juices responsible for OATP2B1-mediated drug interactions.“Eight major flavonoids (naringin, naringenin, hesperidin, hesperetin , phloridzin, phloretin, quercetin, and kaempferol) contained in the juices inhibited OATP2B1-mediated estrone-3-sulfate uptake with IC50 values of 4.63, 49.2, 1.92, 67.6, 23.2, 1.31, 9.47, and 21.3 μM, respectively.”
Major active components in grapefruit, orange, and apple juices responsible for OATP2B1-mediated drug interactions.
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