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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Estrone and Progestins

drug:

Estrone

supplement:

Progestins

Research Papers that Mention the Interaction

Striking differences exist regarding the side effects among the progestins and the combination with EE leads to other reactions related to the E itself and whether the associated progestin counterbalances, more or less, the estrogenic action.
Human reproduction update  •  2006  |  View Paper
These progestins , as well as tibolone, can also block the conversion of estrone to estradiol by the inhibition of the 17beta-hydroxysteroid dehydrogenase type I (17beta-HSD-1).
The Journal of Steroid Biochemistry and Molecular Biology  •  2005  |  View Paper
In another series of studies, it was also demonstrated that various progestins are very active in inhibiting the 17 beta-hydroxysteroid dehydrogenase for the conversion of estrone to estradiol.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology  •  1999  |  View Paper
In another series of studies it was also demonstrated that various progestins are very active in inhibiting the 17beta-hydroxysteroid dehydrogenase for the conversion of estrone to estradiol.
The Journal of steroid biochemistry and molecular biology  •  1998  |  View Paper
Several recent reports have linked the use of estrogenic and progestational hormones during pregnancy with an increased incidence of birth defects.
Journal of the Medical Association of the State of Alabama  •  1977  |  View Paper