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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Estrone and Melatonin

drug:

Estrone

supplement:

Melatonin

Research Papers that Mention the Interaction

On the other hand, melatonin , 5-MI-3-AA, NA-5-HTT, 5-MTT, 5-MTP, HVA, 5-HI-3-AA, VMA, DOPAC, 5-hydroxytryptophol, and MN, but not 3-MT, DHMA, and NMN, at 2 mM, inhibited estrone sulfate uptake mediated by hOAT3.
Journal of pharmacological sciences  •  2003  |  View Paper
Melatonin counteracted the stimulatory effects of estrone sulfate on sulfatase activity and expression and incubation with melatonin decreased the sulfatase activity of tumors from control animals.
Ovariectomy significantly reduced the size and the number of the tumors while the administration of estrone sulfate to ovariectomized animals stimulated tumor growth, an effect which was suppressed by melatonin.
Current cancer drug targets  •  2010  |  View Paper