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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Estrone and Isoflavones

drug:

Estrone

supplement:

Isoflavones

Research Papers that Mention the Interaction

Compared with the control diet, increased isoflavone consumption decreased urinary excretion of estradiol, estrone , estriol, and total estrogens, as well as excretion of the hypothesized genotoxic estrogen metabolites, 16alpha-hydroxyestrone, 4-hydroxyestrone, and 4-hydroxyestradiol.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology  •  1998  |  View Paper
An estrogenic antagonistic effect of isoflavones on bone turnover was observed in premenopausal women who are able to produce more potent metabolites.
Journal of Korean medical science  •  2009  |  View Paper
Isoflavone ISO ) exposure during adolescence has been demonstrated to modulate the estrogenic and proliferative sensitivity of the adult breast tissue.
Archives of Toxicology  •  2012  |  View Paper
Correlation analysis between estrogenic potency and the five major isoflavonoid contents within the previously HPLC-analyzed tuberous samples namely puerarin, daidzin, genistin, daidzein, and genistein revealed a negative result.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas  •  2010  |  View Paper
It appears that ISO can counteract the estrogenic influence of a high dosage of ZEA (2mg/kg).
Animal reproduction science  •  2010  |  View Paper