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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Estriol
supplement:
Progesterone
Research Papers that Mention the Interaction
“The addition of striol to treatment regimens containing progesterone only or human chorionic somatomammotropin (HCS) plus progesterone resulted in improvement in mean glucose disappearance rates following intravenous glucose administration without significant changes in the mean total insulin responses to glucose.”
“These results indicate that estriol and estradiol have different effects on glucose and insulin metabolism and suggest that estriol may modify the diabetogenic tendencies of progesterone and HCS during primate pregnancies.”
Estriol Modification of the Effects of Progesterone and Human Chorionic Somatomammotropin on Glucose Tolerance and Plasma Insulin in Rhesus Monkeys“The concomitant administration of estradiol or estrone with progesterone reproduced the decidual weight observed in intact rats, but estriol in combination with progesterone was only slightly effective.”
“Current hypotheses suggest a surge in the ratio of estriol to progesterone from b1 to N1 marks the impending onset of labor [1–3].”
“A synergistic suppression of cytotoxicity was observed when estrone, estradiol, estriol and progesterone were combined.”
“An additive suppression of cytotoxicity was also observed when estrone, estradiol, estriol , and progesterone were combined.”
“The action of estriol was counteracted by both tamoxifen, an estrogen antagonist, and progesterone.”
“The secretagogue effect of activin on irGnRH release from cultured placental cells was increased by the presence of estriol and reduced by the addition of progesterone.”
“The stimulatory effect of estriol or estradiol was reversed by the concomitant addition of progesterone.”
“Placental steroids estriol and progesterone inhibited transport.”
“Plasma progesterone showed a significant positive correlation with estriol at 34-35 and at 38-39 weeks.”
“The sequential treatment with initial estriol priming followed by estriol and progesterone combined resulted in a slight secretory transformation of the uterine epithelium, observed as an increase in size and number of the apical protrusions of the cells.”
“The 20α-reduction of 4- 14 C-progesterone is inhibited by estriol.”
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