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Last Updated: 2 months ago

Possible Interaction: Estradiol and Tryptophan

supplement:

Tryptophan

Research Papers that Mention the Interaction

During emotion identification, TD heightened activation in the orbital frontal cortex and bilateral amygdala, and this effect was attenuated by estradiol treatment.
During the 2-back condition, TD attenuated activation prior to, but not after, estradiol treatment in the right and left dorsal lateral prefrontal and middle frontal/cingulate gyrus.
Psychoneuroendocrinology  •  2012  |  View Paper
While a similar interaction was observed with placebo treatment, treatment with estradiol attenuated the effects of ACE and TD such that no between or within group differences were observed.
Neuropsychopharmacology  •  2017  |  View Paper
Binding of estradiol to ER beta exposed its tryptophans, whereas estradiol reduced the accessibility of the tryptophans of ER alpha.
Journal of molecular endocrinology  •  2005  |  View Paper
Following oestradiol implant (100 mg s.c.) the prolactin (PRL) response to LTP was significantly enhanced but there was no change in the growth hormone (GH) response to apomorphine.
Journal of psychopharmacology  •  1992  |  View Paper
However, in human receptors it was necessary to mutate both the AGMI sequence and the tryptophan to eliminate potentiation by ethynyl beta-estradiol.
Mutation of this tryptophan eliminates the ability of ethynyl beta-estradiol to potentiate rat receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience  •  2001  |  View Paper