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“Addition of KCl or trypsin to disrupt the 8S ER caused an increase in the amount of extractable oestradiol compared with control values (control = 52 +/- 4.0, high KCl = 91 +/- 4.4, trypsin = 152 +/- 7.5, pg oestradiol/mg protein).”
The Journal of Steroid Biochemistry and Molecular Biology • 1991 | View Paper
“Results: Treatment of isolated exocrine pancreatic cells with estradiol caused stimulation of amylase and trypsin production and inhibition of secretion, while treatment with CCK showed only a minor effect on enzyme production and resulted mainly in a stimulation of secretion.”