“Interfacial coverage of TPGS with increasing TPGS concentration and hindrance of the partitioning of estradiol by the increasing alcohol content might play a role in influencing the permeability of estradiol.”
“Results show that the solubility of estradiol was improved in the presence of TPGS through micellar solubilization.”
“We concluded that micellar solubilization by TPGS was able to improve the solubility of estradiol , but it only had an insignificant influence on the skin.”