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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Estradiol and Sodium Molybdate(Vi)

Research Papers that Mention the Interaction

The addition of molybdate to intact or homogenized cells of the endometrial adenocarcinoma line HEC-1 during incubation with [3H]estradiol ([3H]E2) at 4 C causes substantial increases in cytoplasmic E2 binding levels.
Endocrinology  •  1982  |  View Paper
Conversely, 20 mM molybdate (which prevents the disruption of mature steroid receptor complexes) decreases the neurotrophic activity of FK506, FKBP-52 antibody, dexamethasone, and beta-estradiol.
The Journal of pharmacology and experimental therapeutics  •  1999  |  View Paper
In epithelial cytosol, 10 mM sodium molybdate or 1 mM dithiothreitol enhance [3H] 17 beta-estradiol binding to the secondary sites.
Journal of steroid biochemistry  •  1984  |  View Paper
receptor complex, it blocks the receptor transformation which otherwise occurs during incubation at 28 degrees C. The inhibition by molybdate is apparent both in sucrose gradient centrifugation analyses of estradiol .
The Journal of biological chemistry  •  1980  |  View Paper