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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Estradiol and Selenium



Research Papers that Mention the Interaction

suppressed estradiol levels to a mean 36.3 +/- 3.3% ( SE ) (n = 14) of base line after 4 to 7 days and maintained this suppression in six of seven patients for greater than 14 days.
Cancer research  •  1987  |  View Paper
Additionally, treatment of the cells with 5 ng/mL selenium significantly ameliorated the levels of estradiol , which were decreased in response to heat exposure.
Molecules  •  2020  |  View Paper
Se … estradiol (E2) production, which could be, at least partially, due to increased levels of 3β-hydroxysteroid dehydrogenase(3β-HSD), steroidogenic acute regulatory protein (StAR), p-… monophosphate (cAMP) (P < 0.05); however, follicle-stimulating hormone (FSH) significantly enhanced the production of E2, progesterone (P4) and cAMP (P < 0.05).
Theriogenology  •  2018  |  View Paper
Selenium was also able to increase the plasma levels of LH, FSH, and estradiol toward the control level.
Toxicological sciences : an official journal of the Society of Toxicology  •  2003  |  View Paper
The mitotic index of cultured alpha-cells was significantly decreased [by 67 +/- 5% SE )] 48 h after the addition of estradiol to the culture medium.
Endocrinology  •  1985  |  View Paper
Estradiol significantly decreased the Bmax from 359.7 ± 23.0 fmol/mg protein (mean ± SE ) in ovariectomized rats to 246.2 ± 19.0 fmol/mg protein with the 5 μg/kg dose and to 179.3 ±10.1 fmol/mg protein with the 25 μg/kg dose.
Endocrinology  •  1982  |  View Paper
The selenium-containing estrogens retained the ability to displace [3H]estradiol from the estrogen receptor of rabbit uterine cytosol, although in most instances the displacement was small (3-7% compared to estradiol).
Canadian journal of biochemistry  •  1982  |  View Paper