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Last Updated: 2 years ago

Possible Interaction: Estradiol and Polyunsaturated Fatty Acids

Research Papers that Mention the Interaction

In this study, treatment of steroid-starved ERα-positive MCF-7 and T47D mammary carcinoma cells with 17β-estradiol resulted in increased cellular uptake of the PUFA arachidonic acid (AA) and eicosapentaenoic acid (EPA), important building blocks for cellular membranes, and increased ACSL4 protein levels.
Carcinogenesis  •  2017  |  View Paper
After energy intake was adjusted for, the ratio of polyunsaturated to saturated fat (P:S) in the diet was significantly inversely associated with plasma estradiol and estrone during the luteal phase of the menstrual cycle.
The American journal of clinical nutrition  •  1996  |  View Paper
Furthermore, diet enriched with longer chain n-3 PUFA increased the maternal plasma concentration of progesterone and estradiol during pregnancy (P < 0.05), which coincides with an increase in the number of fetuses sustained till day 18.5.
Reproduction  •  2017  |  View Paper
Estradiol increased 22:5n-3 and total n-3 polyunsaturated fatty acids ( PUFA ) in intact, and decreased 18:2n-6 in BCO rats.
Physiological research  •  2014  |  View Paper
RESULTS Maternal intake of n-3 PU A di ets significantly increased pregnancy 17 bet a-estradiol (E 2) levels (48% increase when compared with high n-6 PUFA diet; P < 0.0045).
Clinical cancer research : an official journal of the American Association for Cancer Research  •  2002  |  View Paper
With any of the two types of microsomal membranes used, the results show that estradiol is more susceptible to be esterified to polyunsaturated fatty acids than saturated ones.
Journal of steroid biochemistry  •  1989  |  View Paper