Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Estradiol and Oxytocin

supplement:

Oxytocin

Research Papers that Mention the Interaction

Treatment of ovariectomized rats with estradiol benzoate or 3β-diol for 4 days increased OT mRNA selectively in the midcaudal, but not rostral PVN compared with vehicle-treated controls.
Endocrinology  •  2013  |  View Paper
Females that received oxytocin pretreatment, as in experiment 1, followed by oestradiol displayed a significant increase in sexual receptivity when compared to females treated with saline and oestradiol or oestradiol only.
In experiment 2 the ability of oxytocin to increase subsequent sensitivity of sexually naive females to oestradiol was tested.
Journal of neuroendocrinology  •  1999  |  View Paper
We also have shown that a similar increase in OT mRNA and peptide synthesis can be stimulated in vitro by physiological concentrations of estradiol.
Advances in experimental medicine and biology  •  1995  |  View Paper
Oxytocin applied to intact corpus luteum stimulates the secretion of progesterone and oestradiol.
Human reproduction  •  1993  |  View Paper
Elevated oestradiol concentrations and bolus injections of oxytocin resulted in a significant increase in the frequency of peristaltic contractions in the early and mid follicular phases, respectively.
In the late follicular phase of the cycle extremely elevated oestradiol concentrations as well as the injection of oxytocin resulted only in an insignificant further increase of peristaltic frequency.
Human reproduction update  •  1998  |  View Paper
These results suggest that oestradiol enhances myometrial responsiveness to oxytocin and other agonists by facilitating phospholipase C activation at a post-receptor level.
Journal of reproduction and fertility  •  1995  |  View Paper
Using an in vitro incubation system, estradiol at physiological concentrations more than doubled the concentration of OT mRNA.
The Journal of clinical endocrinology and metabolism  •  1995  |  View Paper
Oxytocin responsiveness is upregulated by incubating the cells in the presence of oestradiol.
Advances in experimental medicine and biology  •  1995  |  View Paper
Estradiol stimulated synthesis of OT mRNA during in vitro incubation.
The Journal of clinical investigation  •  1993  |  View Paper
Oestradiol-17 beta potentiated the effect of oxytocin.
Acta endocrinologica  •  1984  |  View Paper
Show More