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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Estradiol and Long Chain Fatty Acid

Research Papers that Mention the Interaction

In addition, estradiol inhibited hypothalamic expression of carnitine palmitoyltransferase (CPT1a and CPT1c) and pyruvate dehydrogenase kinase 4 (PDK4), effects that would be expected to enhance the accumulation of long-chain fatty acids and glycolysis.
Brain Research  •  2009  |  View Paper
This enzyme catalyzes the esterification of estradiol with long-chain fatty acids in both liver and extrahepatic tissues.
Biochemical pharmacology  •  2002  |  View Paper
Long chain fatty acids were known to interfere with the binding between rat uterine estrogen receptors and estradiol.
Endocrinologia japonica  •  1986  |  View Paper
The results indicated that estradiol enhanced the methylation of phosphatidylethanolamine and increased the formation of lecithins containing stearic and long-chain polyene fatty acids (20:4 and higher).
Biochimica et biophysica acta  •  1968  |  View Paper