Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 months ago

Possible Interaction: Estradiol and Leucine

supplement:

Leucine

Research Papers that Mention the Interaction

Oestradiol at a concentration of 10 nmol l-1 increased the incorporation of both [3H]thymidine and [3H]leucine but the differences were significantly different from control only for [3H]leucine incorporation.
Journal of reproduction and fertility  •  1995  |  View Paper
The uptake of uridine and leucine is also stimulated by estradiol in a dose-related manner.
Cancer research  •  1982  |  View Paper
Analyses of ion currents demonstrated that EST increased the density of I(Ca, L ) as compared with OVX (P <.05) while PROG decreased it (P <.05).
Analyses of ion currents demonstrated that EST increased the density of I(Ca, L ) as compared with OVX (P <.05) while PROG decreased it (P <.05).
Heart rhythm  •  2012  |  View Paper
E and E+P treatment reduced THDA and PHDA neuron activity under L :D, but did not affect these rhythms under DD.
In TIDA neurons, E or E+P treatment reduced the amount of DA released under L :D and DD and advanced the rhythm of DA turnover.
Brain Research  •  2004  |  View Paper
3) There was an increase in oestradiol concentration from 17.1 +/- 3.0 pmol/l during the L period to 233.7 +/- 86.4 pmol/l during the F period.
Journal of reproduction and fertility  •  1989  |  View Paper
The effects were dose dependent; the half-maximal dose of insulin was about 2 X … and of estradiol was about 5 X 10(-11) M. Treatment with both insulin and estradiol increased … [3H]leucine by 45% compared to controls, incorporation of [3H]… by 65%, and total protein by 50%.
Endocrinology  •  1981  |  View Paper
By 72 hr, transport of both proline and leucine was significantly decreased; incorporation of leucine into proteins and uridine into RNA was significantly reduced by 24 hr after injection of estradiol valerate.
Cancer research  •  1979  |  View Paper