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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
drug:
Estradiol
supplement:
Kaempferol
Research Papers that Mention the Interaction
“This hypothesis was confirmed by in vivo studies which demonstrated that injection of luteolin or quercetin blocked estradiol stimulation of nuclear type II sites in the immature rat uterus and this correlated with an inhibition of uterine growth (wet and dry weight).”
Bioflavonoid interaction with rat uterine type II binding sites and cell growth inhibition.“Similarly, several flavonoids (naringenin, hesperetin, kaempferol , quercetin, rutin, flavone, alpha-naphthoflavone and beta-naphthoflavone) also inhibited rat liver microsomal glucuronidation of estrone and estradiol to varying degrees.”
Effects of tea polyphenols and flavonoids on liver microsomal glucuronidation of estradiol and estrone
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