Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 months ago

Possible Interaction: Estradiol and Kaempferol

supplement:

Kaempferol

Research Papers that Mention the Interaction

This hypothesis was confirmed by in vivo studies which demonstrated that injection of luteolin or quercetin blocked estradiol stimulation of nuclear type II sites in the immature rat uterus and this correlated with an inhibition of uterine growth (wet and dry weight).
Journal of steroid biochemistry  •  1988  |  View Paper
Similarly, several flavonoids (naringenin, hesperetin, kaempferol , quercetin, rutin, flavone, alpha-naphthoflavone and beta-naphthoflavone) also inhibited rat liver microsomal glucuronidation of estrone and estradiol to varying degrees.
The Journal of Steroid Biochemistry and Molecular Biology  •  1998  |  View Paper