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“Administration of ethinyloestradiol and Progynova both reduced urinary hydroxyproline into the pre‐menopausal range, the fail being proportional to the starting value.”
“The rats receiving 1 mug oestradiol per day had a significantly higher specific activity of hydroxyproline in bone compared to the normal and the castrated control rats.”
“The wet weight and the dry, defatted weight of metaphyseal bone were increased by estradiol and the specific activity of hydroxyproline in collagen and proline in the noncollagenous protein was increased.”