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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Estradiol
supplement:
Homocysteine
Research Papers that Mention the Interaction
“The mean change from baseline in homocysteine concentration by both treatments compared with placebo ( ET , -13%; EPT, -10%) was accompanied by a decrease in the concentration of vitamin B6 (ET, -25%; EPT, -38%) and albumin (ET, -7%; EPT, -11%).”
Oral estradiol decreases plasma homocysteine, vitamin B6, and albumin in postmenopausal women but does not change the whole-body homocysteine remethylation and transmethylation flux.“LDL-C (-6%), apo B (-9%), triglyceride (-5%), and homocysteine (-11%) concentrations decreased with estradiol , whereas HDL-C (+14%) increased.”
“ Oestradiol did moderate the relationship between homocysteine and smoking status.”
“At a concentration of 10 μm, 17β‐oestradiol suppressed the H2O2 and homocysteine stimulated G‐proteins in the frontocortical membranes of control women to a greater extent than phytoestrogens.”
“The detrimental effects of 3 mM Hcy on apoptosis and ROS production were partly reversed by bazedoxifene and 17β estradiol.”
Bazedoxifene Ameliorates Homocysteine-Induced Apoptosis and Accumulation of Advanced Glycation End Products by Reducing Oxidative Stress in MC3T3-E1 Cells“We investigated whether 17-beta estradiol may prevent the accelerated rate of endothelial cell detachment and reduced cell viability in cultured endothelial cells challenged with Hcy.”
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