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Possible Interaction: Estradiol and Glutathione



Research Papers that Mention the Interaction

Glutathione had less effect on the formation of 3H2O for the aromatic ring of estradiol than from that of the catechol estrogen where it increased the yield 6-fold.
Journal of steroid biochemistry  •  1990  |  View Paper
During the 6-OHDA induced PD, the level of antioxidant marker such as GSH , ROS and TRAP, found to be significantly modulated by the estradiol.
Pharmacological reports : PR  •  2017  |  View Paper
Estradiol prevents Hcy-induced endothelial cell injury by increasing the intracellular content of GSH.
Journal of cardiovascular pharmacology  •  2002  |  View Paper
The dose of estradiols required for motor neuron protection was greatly reduced by co-administration with glutathione.
Neuroreport  •  2000  |  View Paper
Estradiol (0.1-1.5 mM) produced a dose-dependent depletion of cellular reduced glutathione ( GSH ), whereas it did not alter the glutathione disulfide (GSSG) excretion into the medium.
In rat liver microsomes, estradiol (5-50 microM) significantly interacted with GSH only when an NADPH-regenerating system was incorporated into the medium.
Journal of biochemistry  •  1993  |  View Paper
Glutathione promoted the loss of 3H from C-4 of either estradiol or 2-hydroxyestradiol but had less effect on this reaction at C-1 and inhibited it at C-6,7.
Biochemistry  •  1988  |  View Paper
Ascorbic acid and glutathione inhibited covalent binding of estradiol to macromolecules in the in vitro microsomal system.
Advances in experimental medicine and biology  •  1986  |  View Paper
Treatment of gonadectomized rats with subcutaneous implants of oestradiol and of progesterone increased the rate of oxidation of GSH by about 100%.
The Biochemical journal  •  1969  |  View Paper