Discover Supplement-Drug Interactions
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Possible Interaction: Estradiol and Glutathione
Research Papers that Mention the Interaction
had less effect on the formation of 3H2O for the aromatic ring of
than from that of the catechol estrogen where it increased the yield 6-fold.”
Peroxidase-catalyzed displacement of tritium from regiospecifically labeled estradiol and 2-hydroxyestradiol.
Journal of steroid biochemistry • 1990 |
“During the 6-OHDA induced PD, the level of antioxidant marker such as
, ROS and TRAP, found to be significantly modulated by the
Mechanistic evaluation of neuroprotective effect of estradiol on rotenone and 6-OHDA induced Parkinson's disease.
Pharmacological reports : PR • 2017 |
prevents Hcy-induced endothelial cell injury by increasing the intracellular content of
17-beta estradiol preserves endothelial cell viability in an in vitro model of homocysteine-induced oxidative stress.
Journal of cardiovascular pharmacology • 2002 |
“The dose of
required for motor neuron protection was greatly reduced by co-administration with
Protection of cultured spinal motor neurons by estradiol
Neuroreport • 2000 |
(0.1-1.5 mM) produced a dose-dependent depletion of cellular reduced glutathione (
), whereas it did not alter the glutathione disulfide (GSSG) excretion into the medium.”
“In rat liver microsomes,
(5-50 microM) significantly interacted with
only when an NADPH-regenerating system was incorporated into the medium.”
Estradiol-induced effects on glutathione metabolism in rat hepatocytes.
Journal of biochemistry • 1993 |
promoted the loss of 3H from C-4 of either
or 2-hydroxyestradiol but had less effect on this reaction at C-1 and inhibited it at C-6,7.”
Activation and irreversible binding of regiospecifically labeled catechol estrogen by rat liver microsomes: evidence for differential cytochrome P-450 catalyzed oxidations.
Biochemistry • 1988 |
“Ascorbic acid and
inhibited covalent binding of
to macromolecules in the in vitro microsomal system.”
In vitro covalent binding of 14C-mibolerone to rat liver microsomes.
Advances in experimental medicine and biology • 1986 |
“Treatment of gonadectomized rats with subcutaneous implants of
and of progesterone increased the rate of oxidation of
by about 100%.”
The nature of the sex-linked differences in glutathione peroxidase activity and aerobic oxidation of glutathione in male and female rat liver.
The Biochemical journal • 1969 |
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