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Possible Interaction: Estradiol and Gamma-Aminobutyric Acid

Research Papers that Mention the Interaction

However, co-administration of estradiol and GABA could not protect the kidney against IRI.
International journal of preventive medicine  •  2016  |  View Paper
This suggests that estradiol , via its action on the oestrogen receptor, prolongs the developmental duration of depolarizing GABA.
  •  2009  |  View Paper
Abstract The purpose of this study was to test the capacity of oestradiol to modulate the stimulating effect of a-aminobutyric acid ( GABA ) on serotonin (5-HT) metabolism, previously described in the Suprachiasmatic area of the male rat.
Journal of neuroendocrinology  •  1989  |  View Paper
Furthermore, the amount of both GABA and glutamate content decreased due to high dose of estradiol , while only GABA increased in Pilocarpine treated rats.
European journal of pharmacology  •  2017  |  View Paper
While the levels of CAT, SOD, POD and Estradiol (E2) were significantly increased in the both doses of GABA.
Journal of Ovarian Research  •  2017  |  View Paper
RESULT(S) EV exposure increased 5-HT, DA, NA, and Glu and decreased GABA levels in the VMH-AN.
Fertility and sterility  •  2011  |  View Paper
In the arcuate nucleus, a major regulator of anterior pituitary function, estradiol increases GABA synthesis, altering the morphology of neighboring astrocytes and reducing formation of dendritic spines synapses.
The Journal of Steroid Biochemistry and Molecular Biology  •  2008  |  View Paper
The time needed for the onset of 17 beta-estradiol effect on mIPSC amplitude was approximately 48 h. In the period of 9-11DIV, treatment with 17 beta-estradiol strongly reduced the tonic conductance activated by low GABA concentrations.
Neuropharmacology  •  2007  |  View Paper
Estradiol and the diurnal cycle thus interact to induce shifts in both GABA transmission and postsynaptic response that would produce appropriate changes in GnRH neuron firing activity and hormone release.
The Journal of Neuroscience  •  2007  |  View Paper
In support of our hypothesis, the K+-evoked increase in GABA , but not taurine or glutamate, was significantly attenuated 30 min after treatment with estradiol.
Synapse  •  2006  |  View Paper
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