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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
drug:
Estradiol
supplement:
Docosahexaenoic Acid
Research Papers that Mention the Interaction
“ Estradiol or insulin stimulation increased the pAkt/Akt and pS6/S6 ratios, expression of p-SREBP-1, m-SREBP-1, and FASN, and cell proliferation, and these effects were decreased by DHA.”
Docosahexaenoic acid reduces sterol regulatory element binding protein-1 and fatty acid synthase expression and inhibits cell proliferation by inhibiting pAkt signaling in a human breast cancer MCF-7 cell line“Interestingly, analyses of fatty acid composition of phospholipids revealed that physiological doses of oestradiol increased brain docosahexaenoic acid ( DHA ; 22:6 n‐3) levels.”
Effects of Oestradiol on Brain Lipid Class and Fatty Acid Composition: Comparison Between Pregnant and Ovariectomised Oestradiol‐Treated Rats“Results from this study raise the possibility that co-treatment with 17β-estradiol and DHA may allow a lower dose of 17β-estradiol to be used to provide the same bone-protective effects as when 17β-estradiol is administered alone.”
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