Possible Interaction: Estradiol and Calcium Supplement

“In VSMC both cBA and estradiol , in their free or protein-bound forms induced a steep and immediate rise in intracellular calcium.”

“Sixty minutes of incubation with 17beta-estradiol (10(-5)mol/l) attenuated the tension developed in response to potassium chloride, norepinephrine and calcium.”

“ CA 125 and oestradiol concentrations were negatively correlated, CA 15-3 and oestradiol concentrations were positively correlated.”

“A consequence of this was that estradiol stimulated calcium uptake in enterocytes isolated from LM mice.”

“Pharmacological, but not physiological, concentrations of the estrogen 17β-estradiol reduced Ca ²⁺ spike activity.”

“ Estradiol (E(2)) increases circulating calcium and phosphate levels in fish, thus acting as a hypercalcemic and hyperphosphatemic factor during periods of high calcium requirements, such as during vitellogenesis.”

“Intraperitoneal … estradiol-17beta (E(2) ; 10 microg/g) evoked significant … of circulating plasma levels of calcium and phosphorus and a sustained increases of circulating plasma levels of PTHrP. However, a combined treatment of …(2) and PTHrP(7-34) evoked a markedly lower calcium response compared with E(2) alone.”

“Pretreatment with the gonadal steroid, estradiol , decreases the percentage of neurons responding to KA and decreases the peak amplitude of the calcium transient early in development but has no effect later in development.”

“Taken together, these data suggest that there is a developmental shift in the route of KA-induced intracellular calcium and estradiol modulates KA-induced intracellular calcium to a time restricted to early development, but whether this is the basis of the neuroprotective effect of estradiol remains to be determined.”

“Pretreatment with 17beta-estradiol concentration-dependently inhibited vascular contractions induced by cumulative addition of PE or calcium and almost completely abolished those induced by cumulative addition of Bay K8644, a calcium channel opener.”

“The in vitro release profiles from the cements in simulated body fluid containing 0, 5 and 10 mg/100 ml calcium indicated that estradiol release rate decreased with increasing calcium concentration in the dissolution medium.”

“Moreover, vitamin K2 and estradiol inhibited the increase of Ca and P in the aorta and the elastin fr.”