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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Estradiol and Biochanin A

supplement:

Biochanin A

Research Papers that Mention the Interaction

Though biochanin A , 5-OMe-genistein, 7-OMe-genistein, irisolidone and formononetin slightly induce transcription with hER beta, they act as antagonists in the induction of transcription by 17beta-estradiol.
Biological & pharmaceutical bulletin  •  2002  |  View Paper
However, biochanin A , flavone, or chrysin could inhibit the activity of estradiol in a dose-response manner with IC50 values of 500 nM, 2 microM, and 10 microM, respectively.
Steroids  •  1997  |  View Paper