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Last Updated: 2 years ago

Possible Interaction: Estradiol and Asymmetric Dimethylarginine

Research Papers that Mention the Interaction

The protective effects of estradiol on vasculature may partly be related to a reduction in ADMA levels.
Vascular medicine  •  2006  |  View Paper
However, administration of estradiols reduced the levels of ADMA , total cholesterol, and low-density lipoprotein (LDL) cholesterol and inhibited endothelial senescence and atherosclerosis (all P < 0.01).
Journal of cardiovascular pharmacology  •  2011  |  View Paper
A negative significant correlation was found between estradiol and ADMA (p <0.05).
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology  •  2011  |  View Paper
Pretreatment with 17beta-estradiol (0.1 or 0.3 mg/kg) significantly attenuated inhibition of vasodilator responses to acetylcholine and elevation of both ADMA and MDA concentration by LDL (P < 0.01).
These results suggest that estradiol possesses a protective effect on the endothelium and the protective effect is related to reduction of ADMA concentration by inhibition of lipid peroxidation.
International journal of cardiology  •  2004  |  View Paper