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Discover Supplement-Drug Interactions
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Last Updated: 2 months ago
drug:
Estradiol
supplement:
Androstenediol
Research Papers that Mention the Interaction
“… E directly inhibits 5alpha-R in DP's or whether the effect of estrogens might … conversion of T to the weaker androgens such as androstendione (via 17beta-HSD), androstenediol (via 3beta-HSD) or 17beta-E (via aromatase), thereby diminishing … available for the conversion to DHT, remains to be shown.”
Influence of estrogens on the androgen metabolism in different subunits of human hair follicles.“The apparent KM for oestradiol was 1.59 X 10(-6) M. All three androgens inhibited the metabolism of oestradiol …: ADIOL, 2.05 X 10(-6) M; DHA-S and DHA, 1.59 X 10(-6) M. However, ADIOL … oestradiol for the active enzyme site … sulphate was non-competitive.”
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