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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Erythromycin and Quinidine

supplement:

Quinidine

Research Papers that Mention the Interaction

RESULTS It has … sotalol and quinidine , but also a variety of non-antiarrhythmic drugs such as certain antihistamines, antimicrobial drugs, psychiatric drugs and cisapride, may have the … concern should be drawn to the coadministration of drugs that inhibit the metabolism of these drugs such as ketoconazole, itraconazol and erythomycin.
Acta psychiatrica Scandinavica  •  2003  |  View Paper
Concomitant administration of erythromycin reduced the total clearance of quinidine and its partial clearance by 3-hydroxylation and N-oxidation by 34, 50 and 33%, respectively.
British journal of clinical pharmacology  •  1999  |  View Paper
Since erythromycin and quinidine are known to cause arrhythmias individually, caution and close monitoring are necessary when the drugs are administered concomitantly.
Pharmacotherapy  •  1997  |  View Paper
CONCLUSION Serum quinidine concentrations, electrocardiograms, and other factors that may predispose patients to torsades de pointes, such as hypokalemia and hypomagnesemia, should be monitored closely if quinidine is coadministered with erythromycin.
CONCLUSION Serum quinidine concentrations, electrocardiograms, and other factors that may predispose patients to torsades de pointes, such as hypokalemia and hypomagnesemia, should be monitored closely if quinidine is coadministered with erythromycin.
Clinical pharmacology and therapeutics  •  1995  |  View Paper
Transport studies were conducted with isolated rabbit corneas at 34 degrees C. Efflux of [(14)C] erythromycin was significantly increased in the presence of quinidine , whereas it was unaltered in the presence of VQ and VVQ.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics  •  2006  |  View Paper
There was a statistically significant (p < 0.05) increase in serum BSP levels with CYP3A and P-gp substrates and/or inhibitors, cyclosporine-A, nitrendipine, quinidine , indinavir, daxorubicin, etoposide and erythromycin by 27%, 35%, 32%, 12%, 5%, 22%, and 106%, respectively.
Die Pharmazie  •  2004  |  View Paper