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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Erythromycin and Quinidine



Research Papers that Mention the Interaction

Concomitant administration of erythromycin reduced the total clearance of quinidine and its partial clearance by 3-hydroxylation and N-oxidation by 34, 50 and 33%, respectively.
British journal of clinical pharmacology  •  1999  |  View Paper
Since erythromycin and quinidine are known to cause arrhythmias individually, caution and close monitoring are necessary when the drugs are administered concomitantly.
Pharmacotherapy  •  1997  |  View Paper
Transport studies were conducted with isolated rabbit corneas at 34 degrees C. Efflux of [(14)C] erythromycin was significantly increased in the presence of quinidine , whereas it was unaltered in the presence of VQ and VVQ.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics  •  2006  |  View Paper
There was a statistically significant (p < 0.05) increase in serum BSP levels with CYP3A and P-gp substrates and/or inhibitors, cyclosporine-A, nitrendipine, quinidine , indinavir, daxorubicin, etoposide and erythromycin by 27%, 35%, 32%, 12%, 5%, 22%, and 106%, respectively.
Die Pharmazie  •  2004  |  View Paper