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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Erythromycin
supplement:
Magnesium Cation
Research Papers that Mention the Interaction
“The prolongation of the QT interval by erythromycin was diminished by the elevated magnesium concentration (3.4 mM) at high rates (pacing cycle length 180 vs. 220 ms).”
The Influence of Magnesium on the Electrophysiological Effects of Erythromycin in the Isolated Guinea Pig Heart“… Mg++ or Ca++ … reversed erythromycin inhibition in strains with the basal level of sensitivity (i.e., the Col- parent grown at 25 degrees C or 37 degrees C or the ColV,I-K94+ derivative grown at 25 degrees C) and in those with the plasmid-associated increase in sensitivity.”
Increased sensitivity to erythromycin in Escherichia coli associated with the presence of the ColV,I-K94 virulence plasmid.“Using the chequer-board titration method the synergistic action of ascorbic acid and erythromycin is determined; such a potentiation of erythromycin is also adversely affected by magnesium ions.”
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