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Discover Supplement-Drug Interactions
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Last Updated: 2 months ago
drug:
Erythromycin
supplement:
Glutathione
Research Papers that Mention the Interaction
“RESULTS The increase in IL-8 levels and activity of AP-1 induced by H(2)… cells with EM (5 mug/ml) for 36 h. We also showed that preincubation with EM for … GSH levels, gamma-GCS activity and expression of gamma-… the gamma-GCS-HS 5'-flanking region. ”
Suppression of Oxidant-Induced Glutathione Synthesis by Erythromycin in Human Bronchial Epithelial Cells“ ETM caused reductions in AsA and GSH biosynthesis, ascorbate-glutathione cycle, xanthophylls cycle and antioxidant enzyme activities.”
Toxic effects of erythromycin, ciprofloxacin and sulfamethoxazole exposure to the antioxidant system in Pseudokirchneriella subcapitata.“ Erythromycin may up-regulate the activity of γ-GCS, increasing the expression of GSH , inhibiting the levels of oxidant-mediated IL-1 beta and alleviating hyperoxia-induced lung injury via an antioxidant effect.”
Effects of erythromycin on γ-glutamyl cysteine synthetase and interleukin-1β in hyperoxia-exposed lung tissue of premature newborn rats.“The CED of EMC led to a significant increase in MDA and decreased in GSH concentration in pups' liver tissue in both gestation and LPs and also to a significant increase in MN frequency in both peripheral blood and bone marrow cells of pups.”
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