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Discover Supplement-Drug Interactions
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Last Updated: 2 months ago
drug:
Erythromycin
supplement:
Bergamot
Research Papers that Mention the Interaction
“While approximately 70% of the erythromycin N-demethylation activity was lost during incubation with BG in the reconstituted system, P450 3A4 retained more than 90% of the heme as determined either by UV-visible spectroscopy or by HPLC.”
Inactivation of cytochrome P450 3A4 by bergamottin, a component of grapefruit juice.
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