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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Ergotamine and Vasoconstrictor Agents

Research Papers that Mention the Interaction

In a patient with ergotamine toxicity, these vasoconstrictive properties can lead to frank ischemia.
The Journal of emergency medicine  •  2001  |  View Paper
The above results suggest that ergotamine induces inhibition of the vasopressor sympathetic outflow by activation of prejunctional 5-HT1A, 5-HT1B/1D, α2-adrenoceptors and D2-like receptors in pithed rats.
continuous infusions of ergotamine (1 and 1.8 μg/kgmin) dose-dependently inhibited the vasopressor responses to sympathetic stimulation but not those to exogenous noradrenaline.
European journal of pharmacology  •  2014  |  View Paper
Moreover, the infusions of sumatriptan, ergotamine and dihydroergotamine, but not of magnesium valproate, propranolol or their respective vehicles, dose-dependently inhibited the vasodepressor responses to electrical stimulation.
Life sciences  •  2009  |  View Paper