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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Ergotamine and Phenoxybenzamine

Research Papers that Mention the Interaction

The alpha-blockade caused by ergotamine tartrate and phenoxybenzamine or the beta blockade by propranolol hydrochloride and pindolol resulted in an approximate 50% inhibition of maximum drop in body temperature induced by NaF administration.
Shika gakuho. Dental science reports  •  1989  |  View Paper
However, the responses to the dose of ergotamine were strikingly reduced when the cats were previously treated with the adrenaline antagonists phenoxybenzamine (5 mg/kg) or ergotamine (50 mug/kg).
The stimulant actions of adrenaline, ergotamine and ergometrine were also protected against the blocking action of phenoxybenzamine by treating the muscle with a high concentration of ergometrine instead of adrenaline.
British journal of pharmacology and chemotherapy  •  1962  |  View Paper