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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Ergotamine
drug:
Methoxamine
Research Papers that Mention the Interaction
“In 26 patients migraine was induced in two separate tests and then ergotamine was administered once after methoxamine pretreatment and once after placebo; methoxamine was significantly more effective than placebo in blocking antimigraine effect of ergotamine (p = 0.0055 Fisher's exact test).”
The antimigraine effect of ergotamine: a role for alpha-adrenergic blockade?“The positive inotropic effects of methoxamine were not altered by beta-adrenergic blockade (propranolol), or catecholamine depletion by prior reserpinization, but were completely prevented by alpha-adrenergic blockade (phentolamine or ergotamine).”
Positive inotropic effects of methoxamine: evidence for alpha-adrenergic receptors in ventricular myocardium.
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